Neuroanatomical Correlates of Macrolinguistic Aspects in Narrative Discourse in Unilateral Left and Right Hemisphere Stroke: A Voxel-Based Morphometry Study

Background A growing body of literature has demonstrated the importance discourse assessment in patients who suffered from brain injury, both left and right hemispheres, as represents a key component functional communication. However, little is known about relationship between gray matter density macrolinguistic processing. Purpose This study aimed to investigate this group participants with middle–low low socioeconomic status. Method Twenty adults unilateral hemisphere ( n = 10) or chronic ischemic stroke 10 matched (age, education, status) healthy controls produced three oral narratives based on sequential scenes. Voxel-based morphometry analysis was conducted using structural magnetic resonance imaging. Results Compared controls, showed cohesion impairments, whereas impairments coherence producing macropropositions. Cohesion positively correlated primary sensory area (PSA)/precentral gyrus pars opercularis. Coherence, narrativity, index lexical informativeness were associated PSA/insula superior temporal gyrus. Macropropositions mostly related gyrus, cingulate, motor area/insula. Discussion Overall, present results suggest that hemispheres are implicated processes narrative discourse. Further studies including larger samples various status should be conducted. Supplemental Material https://doi.org/10.23641/asha.14347550